Open AccessAPOL1 Nephropathy Risk Variant Associations with Diseases beyond the Kidney
Author(s) -
Lijun Ma,
Barry I. Freedman
Publication year - 2019
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.10550919
Subject(s) - medicine , nephropathy , focal segmental glomerulosclerosis , kidney disease , glomerulosclerosis , kidney transplantation , renal function , odds ratio , transplantation , kidney , proteinuria , endocrinology , diabetes mellitus
The past decade has seen major developments in our understanding of ancestry-specific rates of CKD and outcomes after kidney donation and transplantation. Genetic association between the G1 and G2 nephropathy risk variants in the apo L1 gene ( APOL1 ) and CKD is recognized as among the strongest in
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