Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population
Author(s) -
Menno Pruijm,
Belén Ponte,
Daniel Ackermann,
Fred Paccaud,
Idris Guessous,
Georg Ehret,
Antoinette Péchère-Bertschi,
Bruno Vogt,
Markus G. Mohaupt,
PierreYves Martin,
Sonia Youhanna,
Nadine Nägele,
Péter Vollenweider,
Gérard Waeber,
Michel Burnier,
Olivier Devuyst,
Murielle Bochud
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04230415
Subject(s) - tamm–horsfall protein , medicine , population , excretion , creatinine , renal function , endocrinology , urinary system , urine , physiology , urology , environmental health
Allelic variants in UMOD, the gene coding for uromodulin, are associated with rare tubulointerstitial kidney disorders and risk of CKD and hypertension in the general population. The factors associated with uromodulin excretion in the normal population remain largely unknown, and were therefore explored in this study.
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