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Background. Sexual dysfunction is a common problem in women with multiple sclerosis (MS). The Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19) is a specific instrument to evaluate sexual dysfunction in MS patients. The purpose of the study was to translate and validate the Ukrainian version of the MSISQ-19. Materials and methods. The original version of MSISQ-19 was translated under a standard procedure. A sample of 126 females with MS completed the questionnaire. Internal consistency was evaluated using Cronbach’s alpha. Convergent validity was established using correlation with the Multiple Sclerosis Quality of Life54 (MSQOL-54) and the Expanded Disability Status Scale (EDSS). Results. Total scale reliability (Cronbach’s α = 0.943) and reliability for the primary (Cronbach’s α = 0.901), secondary (Cronbach’s α = 0.875), and tertiary subscales (Cronbach’s α = 0.918) were high. Disability level, measured with the EDSS, and quality of life, measured with the MSQOL-54, significantly correlated with MSISQ-19 total score. Both physical and mental health-related quality of life on the MSQOL-54 significantly correlated with MSISQ-19 total score, and with primary, secondary, and tertiary sexual dysfunction. Satisfaction with sexual function significantly correlated with MSISQ-19 total score, and with primary, secondary, and tertiary sexual dysfunction. Conclusions. The study findings suggest that the Ukrainian version of the MSISQ-19 is a reliable and valid instrument for sexual function assessment in Ukrainian women with MS. It can be used during routine counseling to introduce the theme of sexuality, to detect sexual dysfunction, provide treatment, and prevent the development of more severe problems and therefore preserve the proper quality of life for MS patients.

Опитувальник щодо інтимного життя та сексуальності у хворих на розсіяний склероз: валідизація та адаптація для україномовного населення