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This study compared fluoride release from three fluoride-releasing dental adhesives (Trial KBF Bond, One-up Bond F, Reactmer Bond) and one conventional dental adhesive (Clearfil SE Bond) for 70 days in vitro. From each material, five disk-shaped specimens (diameter: 9.0 mm, height: 1.5 mm) were prepared and immersed in 5 ml of 10 mM phosphate buffered solution (pH 7.0). After 1, 3, 7, 14, 21, 28, 35, 42, 49, 56, 63 and 70 days, the samples were transferred into new solutions. The fluoride content was determined with a combined fluoride sensitive electrode attached to an ion analyzer. Data were statistically analyzed with ANOVA, followed by Scheffé's test. Reactmer Bond showed the greatest fluoride release over 70 days (280.2 +/- 10.1 micrograms/cm2) among the materials tested. The values for One-up Bond F and Trial KBF Bond were 83.4 +/- 5.3 micrograms/cm2 and 58.6 +/- 1.5 micrograms/cm2, respectively. The values were significantly different among the four groups (p &lt; 0.0001). Clearfil SE Bond showed almost no fluoride release over 70 days.

Fluoride release from newly developed dental adhesives.