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Renal replacement lipomatosis (RRL) is a rare condition, which is characterized by diffuse replacement of renal parenchyma, sinus, and hilum with adipose tissue.(1) It is thought to be associated with physiological as well as several pathological (2,3) In the present case, we found coexistence of RRL with papillary renal cell carcinoma (PRCC). Furthermore, renal tubulopapillary adenomatosis, xanthogranulomatous pyelonephritis (XGP), and multiple renal calculi were also found. A brief review of literature along with probable pathogenesis of such a rare coexistence is presented.

urology journal

Renal replacement lipomatosis with coexistent papillary renal cell carcinoma, renal tubulopapillary adenomatosis, and xanthogranulomatous pyelonephritis: an extremely rare association and possible pathogenetic correlation.