English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Pro

Presents the zaia usage as premium feature

ZAIA

Presents AI Discovery search usage as a premium feature

AI Discovery

Presents AI Discovery explain and summary usage as a premium feature

Content Analysis

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Presents the pdf analysis as premium feature

PDF Analysis

1500 Top-up

3000 Top-up

Zendy Basic

2500 Top-up

Zendy Unlimited

Presents the access of premium content as premium feature

Premium Content

In this paper, we address dynamic controllability of the two different designs of extractive fermentation process, namely one-stage and two-stage designs. The operating conditions that maximize yields and productivity for both designs are determined by optimization using the method of factorial design and response surface analysis. The results show that in terms of the achievable yield and productivity, the performance of the two-stage design is comparable to that of the single-stage, but the former design leads to a significant reduction in the fermentor size required. Furthermore, we analyze the dynamic controllability of the two designs of extractive fermentation process using a so-called control relevant metrics to examine their closed-loop dynamic performance in the face of uncertainty. This analysis reveals that the single-stage design has more favorable dynamic controllability than the two-stage design.

Dynamic Simulation and Optimization of Two-Stage Extractive Alcoholic Fermentation Process: Design Impact on Controllability