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Daily subcutaneous injection into young rabbits of 0.5cc of 3% iodo-casein in NaHCO3 buffer (pH7.8) was continued for seven days. Electrophoretical analyses were made on the sera of the rabbits before and after the injection.The results obtained were as follows:1. Serum albumin decreased, alpha-globuin increased, and gamma-gloulin increased slightly after the injection of iodo-casein.2. Separation of albumin and alpha-globulin peaks in normal rabbit serum is generally incomplete when electrophosesis is performed using phosphate buffer at pH8.0. Separation of the above two peaks in rabbit blood serum was found to be complete under the same circumstances after the injection of iodo-casein.

An Electrophoretic Study of the Alteration in Serum Protein of Rabbits Administered with Iodo-casein