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Background  The COVID-19 pandemic poses a challenge to people’s day-to-day functioning and emotional and physical health, especially among older adults.    Objective  The aim of this study is to analyze gender differences in state anxiety, daily functional self-actualization, and functional cognition as well as the relationships among those factors in older adults during the COVID-19 pandemic lockdown.    Methods  We collected data on the web from a sample of 204 people (102 men and 102 women) aged 60 years and older. In addition to a demographic questionnaire, we used the State-Trait Personality Inventory to assess state anxiety, the Daily Functional Actualization questionnaire to evaluate daily functional self-actualization, and the Daily Living Questionnaire to measure functional cognition.    Results  Significant gender differences were found for state anxiety ( t  202 =−2.36 , P =.02); daily functional self-actualization ( t  202 =2.15,  P =.03); and the functional cognition components: complex tasks ( Z =−3.07,  P =.002); cognitive symptoms that might be interfering ( Z =−2.15 , P =.028); executive functions ( Z =−2.21,  P =.024); and executive function monitoring ( Z =−2.21,  P =.027). Significant medium correlations were found between both state anxiety level and daily functional self-actualization ( r =−0.62,  P <.001) and functional cognition ( r =0.37-0.40 , P <.001). Gender predicted 3% of the variance in state anxiety level, while daily functional self-actualization predicted 41% and complex activities (Daily Living Questionnaire) predicted an additional 3% ( F  3,200 =58.01,  P <.001).    Conclusions  In older adults, anxiety is associated with cognitive decline, which may harm daily functional abilities and lead to social isolation, loneliness, and decreased well-being. Self-awareness and knowledge of gender differences and relationships between common available resources of daily functional self-actualization and functional cognition with anxiety may be strengthening factors in crisis periods such as the COVID-19 pandemic.

Gender Differences in State Anxiety Related to Daily Function Among Older Adults During the COVID-19 Pandemic: Questionnaire Study