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Bladder cancer is the most common malignancy involving the urinary system. The mortality rate in late stages remains high, thus the development of effective biomarkers for diagnosis or prognosis is required in order to improve patient survival rates. Tight junction protein 1 (TJP1) is a membrane-associated protein that helps modulate cell-cell contact. However, the role of TJP1 in bladder cancer progression remains unclear.

Tight Junction Protein 1 Dysfunction Contributes to Cell Motility in Bladder Cancer