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Individuals with type 2 Neurofibromatosis are predisposed for the appearance of schwannomas. In the present study we analyzed the loss of heterozygosity and mutations in the NF2 gene in patients with sporadic Schwannoma without Neurofibromatosis type 2.

Frequency of the Loss of Heterozygosity of the NF2 Gene in Sporadic Spinal Schwannomas