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An immunocomplex of interleukin-2 (IL-2) and its monoclonal antibody, S4B6 (IL-2/S4B6), contributes to antitumor immune systems. We investigated the antitumor efficacy of radiation (IR) combined with IL-2/S4B6 for osteosarcoma.

Radiation Enhances the Efficacy of Antitumor Immunotherapy with an Immunocomplex of Interleukin-2 and its Monoclonal Antibody