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Renal oncocytomas (ROs), and clear cell (RCC) and urothelial carcinomas (UC), are common renal neoplasms. Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the rate-limiting step of NAD + synthesis and its expression is increased in several tumors. Nampt concomitantly regulates hydrogen sulfide (H 2 S)-synthesizing enzyme levels, including cystathionine-β-synthase (CBS).

anticancer research/anticancer research

Increased Nicotinamide Phosphoribosyltransferase and Cystathionine-β-Synthase in Renal Oncocytomas, Renal Urothelial Carcinoma, and Renal Clear Cell Carcinoma