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Objectif: Decrire les facteurs determinants de l’albuminurie chez le diabetique de type 2. Methodes: Nous avons mene une etude transversale, prospective a visee descriptive et analytique. Elle s’est deroulee sur une periode de 06 mois de fevrier a Aout 2014. Ont ete inclus les patients diabetiques de type 2 suivis par un specialiste et ayant fait les dosages nycthemeraux de l’albumine urinaire par la methode immunoturbidimetrique. Ces dernieres sont considerees comme positives a partir de 30 mg/24 h d’albuminurie. La regression logistique, en analyse multivariee, a permis de mesurer l’association entre la survenue de l’albuminurie et ses determinants. Resultats: Cent quatre-vingt-un (181) patients etaient retenus, 86 presentaient une albuminurie positive (soit 47.5%) avec une sex-ratio de 0,7. L’âge variait de 19 a 85 ans. L’IMC variait entre 18.9 et 56.0 kg/m². L’albuminurie positive chez les patients ayant un diabete desequilibre, etait de 57.4% contre 32.9% des diabetiques equilibres (p = 0.001). L’albuminurie positive chez les patients hypertendus etait de 65.2% contre 36.6% diabetiques normotendus (p < 0.001). L’hypercholesterolemie totale etait associee a une albuminurie positive (p = 0.04). L’anciennete du diabete etait egalement associee a une l’albuminurie positive (p = 0.01). Conclusion: L’hypertension arterielle, l’hypercholesterolemie, l’equilibre du diabete et l’anciennete du diabete jouent un role important dans la survenue de l’albuminurie chez le diabetique de type 2. Un controle strict de ces determinants s’avere indispensable. Objective: To describe albuminuria causal factors among type 2 diabetes patients. Methods: We carried out a cross-sectional retrospective study aimed at describing and analyzing the subject matter. It was conducted over a six-month period from February to August 2014. Type 2 diabetic patients regularly seen by a specialist who underwent immunoturbidimetric assay of urine albumin were included in the study. It was considered positive for albuminuria above 30 mg/24h. The multivariate logistic regression analysis enabled us to measure the association between albuminuria and its determinants. Results: One hundred and eighty one (181) patients were selected, 86 had positive albuminuria (47.5%) and the sex ratio was recorded at 0.7. Age ranged from 19 to 85 years. BMI ranged from 18.9 to 56.0 kg/m². Positive albuminuria among uncontrolled diabetes patients represented 57.4% against 32.9% controlled diabetes patients (p = 0.001). Positive albuminuria among hypertensive patients was 65.2% against 36.6% in normotensive diabetic patients (p < 0.001). Hypercholesterolemia was associated with positive albuminuria (p = 0.04). Diabetes seniority was also associated with positive albuminuria (p = 0.01). Conclusions: Blood pressure, hypercholesterolemia, the control of diabetes and duration of diabetes all played a significant role in occurrence of albuminuria among type 2 diabetic patients. It is important to carry out a thorough check on these determinants.

african journal of nephrology

Prévalence et déterminants de l’albuminurie dans le diabète de type 2 chez le sujet noir au Sud du Bénin [Prevalence and determinants of albuminuria in type 2 diabetes among African patients in Southern Benin]