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Advances in bone tissue engineering require new developments in smart materials that allow replacement or regeneration of bone. To accomplish this task, biomedical engineering, specifically engineered biomaterials has been based on nanotechnology once the tissues are natural nanocomposites with perfect architecture. Bone, it is a nanocomposite based on collagen and ceramic, it is bioinspiration focus of the design to new biomaterials for treatment. However, its complexity is enormous tissue because it plays critical functions such as movement and support of other vital organs, storage mineral, homeostasis, regulation of blood pH  and host of multiple cells such as mesenchymal cells and others. Hence, it is a challenge for engineering, designing and construction of materials with features such as biomimetics, bioaffinity by bone cells, as well as complying with the required mechanical properties, as minimum conditions. Some of the latest developments in nanotechnology used in the construction of several nanestructured materials in the area of bone tissue engineering are hinted in this overview.

Técnicas empleadas en síntesis de nanocompuestos en ingeniería de tejido óseo