English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Lichen Planus (LP) is an infl ammatory chronic mucocutaneous disease. Since the etiology of OLP is unknown, efforts to understand the etiology and pathogenecity may lead to improve treatment modalities. Studies have shown the different levels of increase or decrease of various cytokines in saliva, serum or tissue culture of patients with OLP.As saliva originates from blood and its collection is an easy, non-invasive method, so it can be a diagnostic fl uid that has logistical advantages when compared with serum. The purpose of this study was to compare the salivary level of IL17 and IL22 in patients with and without OLP. Saliva of 52 patients with and without OLP was collected. The saliva level of IL17 and IL 22 was measured by using ELISA. Data were analyzed using independent T test, Mann-Whitney and Pearson Correlation test.The saliva concentration of IL 22 was signifi cantly higher in control group than OLP but the difference was not signifi cant between reticular and atrophic-erosive type (P > 0.05).The difference between mean rank of IL17 for OLP and healthy cases and between reticular and erosive-atrophic form was not signifi cant (P > 0.05). There was no correlation between the level of IL17 and IL 22 (P > 0.05). Our fi ndings suggest that IL 22 may have an effect in the pathogenesis of OLP and its protective effect may be decreased in OLP patients.

Comparison of interleukin 17 and 22 in saliva of oral lichen planus patients with healthy people