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ACTN3 is alpha-actinin-3 protein coding genes, and in the gene is found single nucleotide polymorphism (R577X) that encodes a premature stop codon and causes a deficiency of alpha-actinin-3 protein. Athlete performance is determined by muscle performance. Muscle performance consists of muscle strength and muscle endurance. Effects on muscle performance in athletes are showed by the existence of ACTN3 gene polymorphism. RR genotype is useful for strength activity and XX genotype is useful for endurance activity. This study aimed to analyze the relationship between gene polymorphisms ACTN3 with strength and muscle endurance. This study used cross sectional method. The subjects were 77 athletes from Football student activity unit University of Jenderal Soedirman aged 18-25 years, BMI 18.5 to 25.0 kg/m2. Muscle strength was measured using leg strength test, muscular endurance was measured by using half squat jump test for 1 minute, and ACTN3 gene polymorphisms were identified using PCR-RFLP method of research subjects' blood sample. One Way ANOVA test was used to determine the relationship ACTN3 gene polymorphism with strength and muscle endurance. The study indicates there is no significant relationship between ACTN3 gene polymorphism with muscle strength and endurance in athletes Football student activity unit University of Jenderal Soedirman.

Hubungan Polimorfisme Gen ACTN3 dengan Performa Otot pada Atlet UKM Sepak Bola Universitas Jenderal Soedirman