English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Homologous recombination applied to alter specific  endogenous gene, referred as gene targeting, provides the highest level of control over product mutation in cloned genes. In this experiment we showed that by using gene targeting a knock out mutation in IL-2Rβ gene could be generated. The findings of this study indicated that mice lacking the Interleukin-2 receptor β chain (IL2Rβ-/-) had spontaneously activated.T cells. In this study, we investigated abnormal expansion of activated T cells which showed high level of CD69.  These findings suggest that the IL2Rβ-/- mice may serve as animal model for autoimmune diseases and that the accumulation of activated T cell in the future could be usedin clinical setting to cure the diseases. Keywords:T cells, (IL2Rβ-/-), autoimmune

AKTIVASI SPONTAN SEL T LIMFOSIT MENCIT YANG MENGALAMI DEFISIENSI IL2RÎ²