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The vaccination of the elderly is generally ignored and their vaccination is insufficient. However, infectious diseases such as influenza and pneumococcus can be prevented or alleviated by vaccination. The "immune aging" ("immunosenescence") results in a decrease in the functions of the humoral and cellular immune systems in the elderly. Therefore, susceptibility to infections is increasing such as influenza and pneumococcus. Vaccination is effective and protective in these infections as it is important for many infections. If there is no contraindication or immunodeficiency, influenza and pneumococcal vaccinations are recommended for those aged 65 years and over by CDC (Center for Disease Control and Prevention). In this review, the importance of vactination against influenza and pneumococcal infections was discussed in the light of current studies. Yaslilarin asilanmasi genel olarak goz ardi edilmekte olup asilanmalari yetersizdir oysa influenza ve pnomokok gibi enfeksiyoz hastaliklar ve komplikasyonlari, asi ile onlenebilir ya da hafifletilebilirler. Yaslilarda immun yaslanma (immunosenescence) sonucu humoral ve hucresel immun sistem fonksiyonlarinda azalma olmaktadir dolayisiyla/Bu nedenle influenza ve pnomokok gibi enfeksiyonlara karsi hassasiyet artmaktadir. Bircok enfeksiyon etkenine karsi asilanmanin onemi oldugu gibi bu enfeksiyonlarda da asilanma etkili ve koruyucudur. Eger bir kontrendikasyon ya da immun yetmezligi yoksa CDC (Center for Disease Control and Prevention) tarafindan 65 yas ve uzeri olanlara, influenza ve pnomokok asisi onerilmektedir. Bu derlemede, guncel calismalar isiginda immun yaslanma ve bununla iliskili olarak influenza ve pnomokok enfeksiyonlarina karsi asilanmanin onemi tartisildi.

İmmunosenescence and The İmportance of İnfluenza and Pneumococcal Vaccine in Elderly?