English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this study, it is aimed to investigate the effects of caffeic acid phenethyl ester ( CAPE) on bioelement levels of plasma, brain, kidney and liver tissues against malathion toxication in rats. The rats in Control group were fed with standard feed and water. Carrier chemicals given to rats were called Sham group. 0.8 g/kg malathion injected animals named MAL group. 10 µM/kg CAPE injection rats were in CAPE group. To the CAPE+MAL group, first 10 µM/kg CAPE was administered, after one hour, 0.8 g/kg malathion was injected. To the MAL+CAPE group, 0.8 g/kg malathion was injected, after an hour, 10 µM/kg CAPE was administered. Bioelement concentrations in blood and tissue samples were measured using inductively coupled plasma-optical emission spectroscopy (ICP-OES).  From the obtained data, Cu, Zn, Se, Pb, Fe, Mn level changes were remarkable. These elements are important because of their involvement in the antioxidant defense system and metallothioenin structure. The obtained bioelement concentrations show that malathion is an important factor for oxidative stress, and CAPE may an effective agent against lipid peroxidation induced oxidative damage in tissues.

Evaluation of Bioelement Levels in Rat Tissues in Organophosphate Insecticide (Malathion) Toxicity: Effects of Caffeic Acid Phenethyl Ester (CAPE)