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Received: December 22, 2015 Revised: June 16, 2016 Accepted: June 20, 2016 Abstract: Background: There are various methods of formulation of micro and nanospheres such as solvent evaporation, solvent removal, polymerization, hot-melt encapsulation, coacervation, phase/wet inversion, spray drying, spray congealing etc. Amongst these all, solvent evaporation is one of the most widely used, researched, easy, accessible methods and for which many patents have been applied. It is thus imperative to understand the basics of effect of formulation variables and design of solvent evaporation method which will be covered in this review article.

Study of Effect of Different Factors in Formulation of Micro and Nanospheres with Solvent Evaporation Technique