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This guide provides general information on specifying acceptable exhaust and intake designs. It also provides various quantitative approaches that can be used to determine expected concentration levels resulting from exhaust system emissions. In addition, the guide describes methodologies that can be employed to operate laboratory exhaust systems in a safe and energy efficient manner by using variable air volume (VAV) technology. The guide, one in a series on best practices for laboratories, was produced by Laboratories for the 21st Century (Labs21), a joint program of the U.S. Environmental Protection Agency (EPA) and the U.S. Department of Energy (DOE). Geared toward architects, engineers, and facility managers, the guides contain information about technologies and practices to use in designing, constructing, and operating safe, sustainable, high-performance laboratories. Studies show a direct relationship between indoor air quality and the health and productivity of building occupants. Historically, the study and protection of indoor air quality focused on emission sources emanating from within the building. For example, to ensure that the worker is not exposed to toxic chemicals, 'as manufactured' and 'as installed' containment specifications are required for fume hoods. However, emissions from external sources, which may be re-ingested into the building through closed circuiting between the building's exhaust stacks and air intakes, are an often overlooked aspect of indoor air quality

Laboratories for the 21st Century: Best Practices; Modeling Exhaust Dispersion for Specifying Acceptable Exhaust/Intake Design (Brochure)