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The insensible perspiration and the skin temperature were observed on the dorsal region of the human hand througout a year.Generally speaking, the rate of insensible perspiration increased with the rise of air temperature. In some subjects, however, the perspiration was lower in May, June, September and October than that in cooler seasons, while the skin temperature was higher in the former.Observations were made with a reflex vasodilation by application of heat to the other hand or with direct exposure to heat of the designated hand were made. The above mentioned stage with low perspiration could not be found.A tentative suggestion on the significance of keratinization was given.

NOTES ON THE SEASONAL VARIATION OF INSENSIBLE PERSPIRATION IN MAN