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In the SR-poor frog atrial muscle, the presence of transient inward current (ITI) was demonstrated in Ba (0.2-0.3 mM) Ringer after treatment with isoproterenol. A peculiar slow inward current (IU) superposing on the tail of the delayed outward current (IX) was also elucidated at the maximum diastolic potential level, which may enhance the pacemaker depolarization.

A further study on the membrane currents related to Ba-induced pacemaker in the bullfrog atrium.