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ATPase reaction profiles of intrafusal fibers in the muscle spindle of the soleus muscle of 135-week-old rats were examined. Nuclear bag1 fibers contained an acid- and alkaline-labile form of the enzyme or an acid-labile and alkaline-stabile form, nuclear bag2 fibers contained an acid- and alkaline-stabile form, and nuclear chain fibers contained an acid-labile and alkaline-stabile form. These results indicate that the enzyme histochemical heterogeneity of intrafusal fibers is well-preserved during ageing.

Histochemical properties of intrafusal fibers in the soleus muscle of the aged rat.