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To investigate the relationship between motor endplate size and muscle fiber diameter, analyses of 125I-alpha-bungarotoxin autoradiographs and acetylcholinesterase staining were performed in different muscle groups of the rat. These revealed 1) there is a linear correlation between endplate size and fiber diameter in each muscle group, and 2) each muscle group has a characteristic ratio of endplate size to fiber diameter; the ratios were markedly higher in extraocular muscles than in limb muscles.

The relationship between motor endplate size and muscle fiber diameter in different muscle groups of the rat.