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Encephalitis by Herpes Simplex virus type-2 in adults is rare and has been described as part of a disseminated infection in settings of immunosuppression, pregnancy being one of them. The virus was isolated from CSF of a young female, who during puerperium, presented with hepatitis, encephalitis and subsequently developed persistent vegetative state. Case history of another woman at term pregnancy is described who had similar illness but virological proof could not be obtained.

Herpes simplex virus type-2 encephalitis in peripartum period preceded by hepatitis.