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We herein report the first case of low-dose oxygen therapy for pneumatosis cystoides intestinalis (PCI) using PaO 2 as a therapeutic index to prevent acute exacerbation of interstitial pneumonia. An 86-year-old man was admitted to our hospital with abdominal distension. PCI was diagnosed by abdominal computed tomography. Low-dose oxygen therapy was started to avoid acute exacerbation of interstitial pneumonia. The oxygen dose was adjusted so that the PaO 2 value was approximately 100 mmHg. After seven days of treatment, the colon gas had disappeared, and no acute exacerbation of interstitial pneumonia was observed. A PaO 2 value around 100 mmHg is effective for PCI without inducing acute exacerbation of interstitial pneumonia.

internal medicine

PaO&lt;sub&gt;2&lt;/sub&gt;-guided Low-dose Oxygen Therapy for Pneumatosis Cystoides Intestinalis to Prevent Acute Exacerbation of Interstitial Pneumonia