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Heavy drinkers have a high incidence of chronic pancreatitis (CP), but the mechanism of alcohol-related CP is largely unknown. Exocrine pancreatic insufficiency exists in about 90% of the patients with cystic fibrosis (CF), which results from an abnormal cystic fibrosis transmembrane conductance regulator gene (CFTR).

internal medicine

Homozygous (TG)11 Allele in Intron 8 of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene has a Protective Role against Bicarbonate Decrease in Pure Pancreatic Juice among Japanese Male Alcoholics