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Clinical liver transplantation and its major problem The indications of liver transplantation are divided into three groups: acute hepatic failure representing fulminant hepatic failure ( 1), chronic hepatic failure representing liver cirrhosis and metabolic disease representing Wilson's disease and citrullinemia. It is accepted that the clinical outcomeof liver transplantation is good and beneficial in both cadaveric and living related-donor (2) liver transplantations for irreversible liver diseases. In spite of the good clinical results, there are many problems following the liver transplantation. We have recurrence of primary disease, re-infection of hepatitis viruses, metastasis of hepatocellular carcinoma toward graft liver, posttransplant lymphoproliferative disorder, chronic rejection and opportunistic infection. Furthermore, the most important complication after liver transplantation is brain damagewhich affects the recipient's quality of life.

Does Brain Damage (Hepatic Encephalopathy) Improve without Any Complication and Sequellae after Liver Transplantation?