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As a part of multi-level model of accumulation of functional disorders in the human body under the influence of environmental factors, the sub-model of “meso-level” of digestive system is being developed. The article highlights the tasks of reconstruction of 3D model of antroduodenal area of the gastrointestinal tract and evaluation of nodes dislocation of the computational grid at the passing of peristaltic wave in gastric antrum and pyloric sphincter motor activity. The observed approaches could be applied in health risk assessment at peroral exposure to chemicals.

3D modeling of antroduodenal zone motility of digestive track for the purpose of health risks evaluation with peroral exposition to chemicals