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The present study was designed to evaluate the protective effect and treatment effect of Alpha lipoic acid administration on cardiac necrosis markers, some electrolytes and cardiac tissue antioxidants in myocardial necrosis induced experimentally in ratsThe investigated serum and cardiac biochemical parameters were: A) Serum levels of creatine kinase (CK) ,creatine kinase MB (CK-MB), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), total protein (T.P), albumin (Alb), glucose, calcium (Ca), sodium (Na), potassium (K), phosphorus (P). B) RBCs glucose 6 phosphate dehydrogenase (G-6-PDH). C) Cardiac antioxidants (SOD and CAT) and cardiac oxidant (MDA).

Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction