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The standard of care for localized muscle-invasive bladder cancer is radical cystectomy1. However, although this procedure is associated with excellent local control, it is not without risk of complications and, sometimes, poor quality of life results. Although significant improvements in continent urinary diversions have been made recently, there is still no substitute for the patient's own fully functional bladder.

Prognostic and Predictive Value of P53, Bcl2, Rb and Egfr for Bladder Preservation in Invasive Bladder Carcinoma Treated by Trimodality Approach