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Background: Tobacco overtaking, sedentary lifestyle and low fitness considered as the main risk factors for diseases that leads to death, such as, coronary heart disease, stroke, obesity and hypertension which are the most common causes of morbidity and mortality.Aim of Study: The purpose of this study was to find out the effect of interval training on nicotine in male smokers.Subject and Methods: The study was conducted on thirty smokers in New Cairo Hospital started at August 2017 and had been finished at December 2018, their age ranged from 20 to 40 years their BMI ranged from 25 to 29.9kg/m2 all subjects were thoroughly evaluated before and after the exercise protocol application. Initial assessment were included measurements of body weight, body height, and nicotine blood levels, all were free from musculoskeletal disorders or cardiovascular disorders, then subjects started treatment program as following, performing a supervised running on treadmill in pattern of high intensity interval training for 30 minutes, 3 sessions per week for 8 weeks. Each training session was consisted of 5 minutes of warming-up walking, 10 minutes of high intensity interval training consist of 2 repeats of (1min running at 85-95% of MHR then followed by 4min recovery at 60-70% of MHR), and ended with 5 minutes of cool-down walking.Results: Statistical analysis showed a significant improve-ment (decrease) in cotinine level (nicotine) by 39.94%.Conclusion: It is recommended for smokers to participate in high intensity interval training to decrease smoking craving, and then smoking cessation.

Nicotine Response to Interval Training in Male Smokers