English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the zaia usage as premium feature

ZAIA

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the access of premium content as premium feature

Premium Content

Zendy Tools

Zendy Open

Background: Autoimmune hepatitis is a complex disease that represents a challenge in diagnosis and management due to the diversity of the clinical presentation, now recognized as a relatively rare disease predominantly affecting females. Aim of Study: This study aimed to describe the frequency and presentation of autoimmune hepatitis and type of autoantibodies among patients who attend a private clinic in Aden Yemen. Patient and Methods: A prospective study carried out in a private clinic over a period of two years, from June 2016 to June 2018, all of 60 patients had raised liver enzymes and Antinuclear Antibodies (ANA), Anti-Smooth-Muscle Antibodies (ASMA) titers 1:80 or above upper limit, Anti Liver Kidney Microsomal (LKM-1). Titer 1:40 or above upper limit, and IgG more than 10 times of normal have been included in this study, all patients rejected liver biopsy. Results: 60 subjects were recruited into study. The sex distribution showed a prominence of female gender (63%) versus (36%) being male. Residency distribution revealed that, the majority of our patients came from shabwa governorate (53.3%). The frequency of chronic hepatitis is 40% while each of acute hepatitis and liver cirrhosis constituted 30% of patients, antinuclear antibodies was elevated in 73.3% antismooth-muscle antibodies in 25% while anti liver kidney microsomal antibody was elevated only in 1.6%. Conclusion: Autoimmune hepatitis frequency, presentation and type of autoantibodies among Yemeni patients do not remarkably differ from studies carried out world wide.

Frequency and Presentation of Autoimmune Hepatitis and Type of Autoantibodies among Yemeni Patients Attending Private Medical Clinic in Aden Yemen