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Toxicity effects of tow insect growth regulators (IGRs) chlorfluazuron and flufenoxuron alone and their combinations with oils at quarter, half and recommended rates were studied by using second (2 nd ) and fourth 4 th larval instars of the cotton leafworm, Spodoptera littoralis. (Boisduval). The results achieved in this study can be summarized in the following, chlorfluazuron was more toxic on both 2 nd and 4 th larval instars than flufenoxuron when used alone at quarter, half and recommended rates. Concerning the effect of binary mixtures of the tested compounds at half-and quarter recommended dose, chlorfluazuron when mixed with Kz oil exhibited highly mortalities against 2 nd i nstar larvae of field strain of S. littoralis which caused 96.17% as residual effect compared with chlorfluazuron when used alone (91.45%) at half recommended dose. While, chlorfluazuron + Hopa oil was recorded high mortality 94.47% at quarterrecommended dose as residual effect compared with chlorfluazuron when used alone (81.23%) at the quarter recommended rate .Also, Flufenuxuron + Hopa oil has the highest residual activity (95,25%) when compared to 79.10% for flufenuxuron alone at the half recommended rate. While, flufenuxuron + Misrona oil was recorded high mortality 82.93% as residual effect compared with 73.01% for flufenuxuron when used alone at the quarter recommended rate . Also, regarding the chlorfluazuron when mixed with Kz oil exhibited highly mortalities against 4 th instar larvae of field strain of S. littoralis which caused 95.40% as residual effect compared with chlorfluazuron when used alone (92.94%) at the half recommended rate. While, chlorfluazuron + Kz oil was recorded high mortality 92.62% as residual effect as compared with chlorfluazuron when used alone (80.48%) at the quarter recommended rate .The data also confirmed that, flufenuxuron + Hopa oil has the highest residual activity (93, 5%) when compared of 71.53% for flufenuxuron alone at the quarter recommended rate . While, flufenuxuron + Misrona oil was recorded high mortality 79.29% as residual effect compared with 70.96% for flufenuxuron when used alone at the quarter recommended rate . It could be concluded that,the oils when mixed with IGRS enhanced the toxicity effect of IGRs against 2 nd and 4 th instar larvae of field strain of S littoralis.

TOXICITY OF SOME INSECT GROWTH REGULATORS (IGRs) AND THEIR BINARY MIXTURES WITH OILS ON COTTON LEAFWORM LARVAE SPODOPTERA LITTORALIS (BOISD)