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Purpose to assess the value of the multi-parametric MRI of prostate as a non invasive biomarker in differentiation between different prostatic lesions. Patients and Methods: Prospective study was done on 30 male patients complaining from lower urinary tract symptoms with elevated prostatitic specific antigen ( PSA ) level or abnormal digital rectal examination ( DRE ). Results: MRI was good positive test in diagnosis of malignancy with sensitivity (100%) and specificity (81.1%) also it consider good positive for diagnosis of isolated benign prostatic hyperplasia (BPH) with sensitivity (89 %) and specificity (80%). Conclusions: Prostate imaging reporting and data system. (PIRADS) is an efficient system for the diagnosis of different prostatic disease and depending on all sequences give better results than relying in the diagnosis on individual sequences.

The role of multi-parametric magnetic resonant imaging as a non invasive biomarker for differentiation between different prostatic lesions