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Obesity is a growing health problem which is accompanied with increasing the rate of morbidity and mortality. The fact that obesity is the state of adiponectin deficiency makes this hormone a very tempting target for possible therapeutic interventions focusing. Most slim reduction weight cause potentially serious side effects. Herbal medical is a growing area of alternative medicines nowadays. Accordingly, the present study was aimed to identify the effect of different doses of fennel, marjoram, sage and ginger on body weight, adiponectin , leptin ,glucose and lipid profile for rats suffering obesity. Aqueous extract of four herbs (Fennel, marjoram, sage and ginger ) were prepared. 60 male albino suffering from obesity were treated with different doses of Aqueous extract of the previous four herbs. The results indicated that, best results in body weight gain % recorded for the group which treated with 11⁄2 ml of fennel. Groups treated with high dose of four tested herbs tended to have lower in total cholesterol, triglyceride, LDL-c VLDL-c and serum glucose. On contrast with increasing the herbal dose the HDL-c has been also increase. Group treated with high dose of ginger tended to have the best results for all tested factor ( lipid profile, serum glucose). All tested herbs decrease the level of lept in hormone and increase the level of serum adiponect in hormone. Accordingly, all tested herbs specially ginger can use for reduction of body weight.

The Effect of Some Herbal Beverages on the Level of Adiponectin Hormone, Glucose and Lipid Profile of Obese Rats