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Several investigators have reported that age at onset has a modifying effect on disease expression. In comparison with younger patients, elderly patients with SLE are reported to have a more insidious onset of disease and less common occurrence of the classic manifestations of SLE1. Thus the correct diagnosis is often not made for several years and is established only after extensive diagnostic evaluation2. It has also been noted that certain features of SLE usually associated with severity, such as nephritis or central nervous system dysfunction, are less common in patients with older-onset SLE3. .

A case of late Onset Systemic Lupus Erythematosus with severe myalgia