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Several studies has been reported on1,3,4- thiadiazole and their derivatives because of their wide range of therapeutic activities. Many drugs containing thiadiazole derivatives are available in market such as acetazolamide, methazolamide, sulphamethazole, cefazoline. This review article highlights the recently synthesized 1,3,4-thiadiazole possessing important therapeutic activities and Computational Studies.

A Review on Synthesis, Therapeutic, and Computational Studies of Substituted 1, 3, 4 Thiadiazole Derivatives