English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The black seed (Nigella sativa), a member of the Runuculaccae family, is an annual plant growing in countries bordering the Mediterranean sea (Jansen, 1981). It is one of the native plants that arc widely distributed in Egypt (Hashem and EI· Kiey, 1982). In Arabian folk medicine, the black seed and its constituents, especially oils, have been used for treatment of many diseases such as diabetes. hypertension, bronchial asthma and rheumatism (Hashem and El-Kiey, 1982). Moreover. Nigclla sativa seeds are digestive stimulants as well as carminative. diuretic, ami-hclmintic. antitumor activity (Hassan and EI-Dakhakhny, 1992). an immune modulating effect (El-Kadi et al., 1987) and cytoprotectivc effect on tissues exposed to cytotoxic agents (El-Kadl et at, 1987). It is reponed that the seeds contain fixed and volatile oils which contain thyrnoquinone (El-Dakhakhny, 1995). It has been reported that thymoquinone protects organs sgainst oxidative damage induced by a variety of free radical generating agents (EI-Tahir et at, 1993). It was reported also that thyrnoquinone has an anri-Inflammatory activity in rats and inhibits eicosanoids generation in leukocytes (Ligumsky et al., 1995) and non enzymatic peroxid.nion in brain phospholipid liposornes (Kolbasa et al., 1998). Thymoquinone reduces free radical generation especially hydroxyl radicals. These hydroxyl radicals arc known to playa major role in the pathogenesis of gastric mucosal ulcer (Kolbasa et at, 1998). Indomethacin is widely used in treating many diseases as rheumatic diseases, gout and fevers. Many roxie and side effects can be seen due to the use or abuse of indomethacin, especially those related to the gastroimestinal tract due to its local

STUDY OF THE NIGELLA SATIVAL OIL ON GASTRIC SECRETION AND GASTRIC MUCOSAL LESION INDUCED BY ORAL INDOMETHACIN IN ALBINO RATS