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Mosquitoes can transmit diseases to about 700 million people all over the world (Taubes, 1997). Culex species can transmit a nematode worm (Wuchereria bancrofti), which is responsible for filarial disease (Holder, 1999). About 3492 species of mosquito are recorded, 100 species of them are vectors and can transmit many diseases to humans and mammals (Ghosh et al. 2012). Mosquito control remains difficult since there is no drug or vaccine. Culex species control is an important step to prevent disease outbreaks. The control of the Culex species at the larval stage has been more convenient since the insect is more sensitive. Moreover, the insecticide application is in a defined area, which decreases environmental contamination. Synthetic insecticides were used for many decades to control mosquito larvae, which led to the development of insect resistance. ARTICLE INFO ABSTRACT Article History: Received: Dec. 5, 2020 Accepted: Jan. 5, 2021 Online: Jan. 9, 2021

Insecticidal Activity and Biochemical Study of the Clove Oil (Syzygium aromaticum) Nano- Formulation on Culex pipiens L. (Diptera: Culicidae)