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The development of feeds for aquaculture has been traditionally based on fishmeal as the main protein source because of its high level of protein content and essential amino acid profile (Tacon, 1993; Watanabe, 2002; El-Saidy and Gaber, 2004). However, the global fishmeal has increased in price more than twice in recent ARTICLE INFO ABSTRACT Article History: Received: Feb. 10, 2020 Accepted: March 28, 2020 Online: April 2020

egyptian journal of aquatic biology and fisheries

Effect of Protease and Prebiotic mixtures with Free Fishmeal Diets on Physiological Responses and Histological Examinations of the Red Tilapia, Oreochromis sp.