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The River Nile is the donor of life to Egypt and represents the principle freshwater resource that meets nearly all demands for drinking water and irrigation (Korium and Toufeek, 2008 and Ali et al., 2008). River Nile water quality has been steadily deteriorating over several decades due to the dumping of anthropogenic inputs and untreated effluents. The Nile runs through a narrow valley (1000 km long). Subsequently, it is bifurcate at a distance of 25 km (north of Cairo) into the Rosetta and Damietta branches forming a delta (Abdel-Satar et al., 2017). Rosetta Branch passes cutting six governorates; El-Kalubia, El-Menofiya, El-Giza, El-Gharbia, Kafr ElShiekh and El-Boheira `over a length of about 236 km on the western boundary of the Nile Delta from Egypt's Delta Barrage with an average width of 180 m and depth from 2 to 4 m (El Gammal and El Shazely, 2008). ARTICLE INFO ABSTRACT Article History: Received: Feb.28, 2020 Accepted: March 22, 2020 Online: March 15, 2020

Impact of the water quality of El-Rahawy Drain on some g enetic and histopathological aspects of Oreochromis niloticus