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The coastal areas and estuaries are the most exposed areas to chemical pollution. (Almeida and Soares, 2012). In many countries, increasing of the industrialization and agricultural activities contribute to an increasing of discharge of chemical pollutants into the ecosystem, which lead to increase in metals levels in the natural waters that causing damage of fresh and marine habitats (Muhammad et al., 2011; El Nemr, 2012). Trace metals exist naturally in the earth’s crust. Some of them are essential for biological systems, since they participate in numerous enzymatic processes (Pellerin and Amiard, 2009). On the other hand, trace metals such as cadmium, lead and mercury are generally toxic for organisms, even at low concentrations (Stankovic and Jovic, 2012).Their bioaccumulation in tissues lead to intoxication, decreased fertility, cellular and tissue damage, cell death, dysfunction of a variety of organs and induce cancer in humans (Benavides et al., 2005; Nordberg, 2010). Bivalve molluscs can take up contaminants from sediments, suspended particulate materials, water column and also food sources (Laffon et al., 2006). They have been widely used for many years as bioindicator organisms in monitoring of chemical ARTICLE INFO ABSTRACT Article History: Received: Sept. 27, 2020 Accepted: Nov. 8, 2020 Online: Nov. 9, 2020

Impact of the size of commercial bivalves on bioaccumulation and depuration of heavy metals