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Results: Patients of CPL and RPL groups showed significantly high serum TNF-a and IL-6 levels with significantly lower serum IL-10 levels than women of NP group with significant difference between CPL and RPL groups. Serum AAT levels were significantly lower in CPL group than RPL and NP groups with significantly lower levels in RPL than NP group. High serum TNF-a and low AAT levels showed high positive predictive value (PPV) and sensitivity, respectively, for possibility of presence or recurrence of PL

the egyptian journal of fertility and sterility

Disturbed inflammatory/anti-inflammatory milieu and activation of Primary Phase Reactants may underlie Development and Recurrence of First trimester Pregnancy Loss.