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Objective:: To compare die effect of two different limes of ousel of lutcal phase support on ongoing pregnancy rale in infertile patients undergoing treatment with GnRH down-regulated IVF and embryo transfer (IVF/ET). Design: prospective randomized trial. Setting : Assisted reproductive tecbnology program at the shatby university hospital for women , and Madina infertility Private center in Alexandria. Patients : one hundred and forty patients undergoing IVF-ICSI program. Intervention: All palicnls planned to undergo Iheir first IVF treatment cycle were randomly allocated lo receive parentral progesterone as luteal support at two different lime points, that is, the clay before embryo transfer (ET) and til the day of ET. The primary endpoint of ibis study was ongoing pregnancy rale. Main outcome Measures: Clinical pregnancy rates. Results : A total of 140 women were randomized; 70 were allocated lo the day before embryo transfer group , and 70 lo the group of the day of ET. An ongoing pregnancy rate was 22.7% in the day before embryo transfer group versus 23.6% at the day ET group, respectively. Conclusion : We could not identify, within the chosen time points and within the sample size, a specific implantation window period in which an optimal endometrial receptivity yields the highest pregnancy rate.

EFFECT OF STARTING PROGESTERONE SUPPORT ON THE DAY BEFORE VERSUS THE DAY OF EMBRYO TRANSFER ON THE OUTCOME OF ICSI CYCLES