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Objective: To evaluate the difference in uterine artery impedance to hlood now among women with unexplainedinfertility and recurrent pregnancy loss in the midlutcal phase or spontaneous cycles.Design: Prospective study.Setting: Department of Obstetrics and Gynaecology, Shatby University Hospital, Alexandria.Subjects: Thirty women with unexplained infertility (group A), twenty women with a history of recurrent pregnancyloss (group B) and twenty fertile controls (group C).Interventions: Midluteal sonographic evaluation of uterine artery impedance to hlood now and endometrial thickness.Main outcome measures: The mean right and left uterine artery pulsatility index (PI values).Results: PI values did not differ significantly in unexplained infertility (1.83 ± 0.55) and recurrent pregnancy loss (1.73± 0.49) compared to controls (1.84 ± 0.48). However, endometrial thickness was significantly decreased inunexplained infertility (9.17 ± 1.93 mm) and recurrent pregnancy loss (9.1 ± 2.13 mrn) compared to controls (12.6 ±2.22 mm). There was no significant correlation between PI values and endometrial thickness in all the studied groups(p > 0.05). However there was a significant positive correlation between PI values and age (r = 0.4666, p = 0.001).Conclusion: Evaluation of uterine impedance hy pulsed Doppler ultrasound in patients with unexplained infertility andrecurrent miscarriage is considered an investigational technique without sufficient proven clinical benefits.

MIDLUTEAL COLOUR DOPPLER ULTRASONOGRAPHIC ASSESSMENT OF UTERINE BLOOD FLOW IN UNEXPLAINED INFERTILITY AND RECURRENT MISCARRIAGE