English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: In spite of the fact that the medical care has been extremely improved, the survivalrate of patients diagnosed with Squamous cell carcinoma is still decreased . Doxorubicin (DXR)is one of the most effective anti- squamous cell carcinoma drugs. This drug has a dangerous sideeffects. Natural products can lighten the DXR- induced side effects, without compromising itsantitumor efficacy. The consumption of extra virgin olive oil (EVOO ), appeared to be related tofewer malignant tumor occurrences. Aim of the study: The objective of the present study was toevaluate the effect of EVOO when used alone and, more interestingly, when combined with DXR,for 48 hours, on lingual squamous cell carcinoma cell line (SCC25). Materials and methods: SCC25was used in this study, it was divided into four groups. Group I (control), group II (DXR treated),group III (EVOO treated) and group IV (EVOO +DXR treated). Results: there was significantdecrease in MMP-1, VEGFR-2 expressions as well as migration and invasion between the testgroups and the control group. Conclusion: EVOO is a promising anticancer compound when usedalone or in combination with DXR.

Synergistic Effect of Combined Treatment with Extra Virgin Olive Oil and Doxorubicin on squamous cell carcinoma cell line