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Aim: To evaluate the efficiency of using platelet rich fibrin (PRF) in small chronic periapicallesions with simultaneous immediate implant placement in maxillary anterior esthetic region.Patients and Methods: Seven cases with small size periapical lesions in the upper anterioraesthetic zone need immediate implantation were selected. After flapless tooth extraction andcurettage of the lesion, platelet-rich fibrin (PRF) was applied in the bony defect and TIXOS implantwas inserted simultaneously. CBCT was used immediately and 6 months post implantation toevaluate the mean of bone density in the defect area.Results: There was increase in the mean of bone density after six months post implantation andit was statistical significant.Conclusions: Platelet-rich fibrin in patients with chronic periapical lesions allow proper bonehealing with immediate implant placement in maxillary anterior aesthetic zone.

Effect of Platelet Rich Fibrin on Bone Healing in Small Periapical Lesions with Simultaneous Immediate Implantation in Maxillary Aesthetic Zone