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Aim of the study: This study aimed to evaluate the effect of hyperbaric oxygen therapy on success rate of implants used to retain mandibular overdentures and possibility of osteonecrosis of the jaw in Bisphosphonate treated osteoporotic patients. Materials and methods: Eight systemic free patients were selected as control group (CG) and eight osteoporotic patients treating with Bisphosphonate drugs orally more than two years were selected as study group (SG). For both groups, patients received mandibular implant retained overdentures with locator anchors following two stage surgical protocol. Patients of study group were received Hyperbaric oxygen thereby (HBO) after the first stage surgery, while those of control group were not received (HBO). Peri-implant marginal bone height and density were evaluated at six months (T6), twelve months (T12) after insertion using Cone Beam Computed Tomography (CBCT). Results: No failure of dental implants were recorded with 100% cumulative survival rates for both groups. Both groups showed increase in bone density and decrease in marginal bone height through a period of one year follow-up. However, the group that received HBO therapy showed less marginal bone loss and more increase in bone density than the control group. Conclusion: Hyperbaric oxygen therapy is valuable and effective treatment for osteoporotic treated Bisphosphonate patients receiving implant retained mandibular overdentures as it eliminate the possibility of Bisphosphonate associated osteonecrosis of the jaw (BONJ), reduces bone loss and increase bone density around dental implant resulting in normal survival rate.

EFFECT OF HYPERBARIC OXYGEN THERAPY ON osseointegration OF DENTAL IMPLANT RETAIN MANDIBULAR OVERDENTURES WITH BISPHOSPHONATE TREATED PATIENTS